
PRX Derm Perfexion in Naples, FL
PRX Derm Perfexion® is a no-needle skin rejuvenation treatment designed to brighten, firm and improve overall skin quality without traditional peeling or downtime. It works beneath the surface to stimulate renewal, leaving skin looking smoother, firmer and more radiant.
The experience
What it’s actually like
PRX Derm Perfexion® is a biorevitalization treatment designed to leave the skin looking firmer, smoother and more radiant without traditional peeling or downtime.
The formula is carefully massaged into the skin layer by layer, allowing its 33% TCA and hydrogen peroxide technology to work beneath the surface while leaving the outermost layer of skin intact. You may feel a brief warmth or tingling as each layer is applied, but the treatment is quick and well tolerated.

The science, briefly
How it works
PRX Derm Perfexion® combines 33% TCA with hydrogen peroxide to stimulate skin renewal and support new collagen beneath the surface without causing traditional peeling. Kojic acid helps brighten the complexion and improve uneven tone. The formula is applied in customized layers, allowing us to tailor the treatment to your skin and its needs.
Prep
We begin by thoroughly cleansing and drying the skin to prepare it for treatment.
Apply
PRX Derm Perfexion® is carefully massaged into the skin layer by layer, with each application customized based on the treatment area and your skin’s needs.
Experience
You may feel a brief warmth or tingling as the formula is applied, which typically settles quickly. No numbing is needed.
Finish
Once treatment is complete, we apply PRX-specific skincare followed by SPF to hydrate, soothe and protect your skin.
Straight answers
What to expect from results
PRX Derm Perfexion® delivers an immediate glow while supporting continued improvement in skin tone, texture and firmness over time.
Where it shines
PRX is ideal for dullness, uneven tone, loss of firmness and skin that simply needs a refresh. Many clients notice brighter, smoother and more radiant-looking skin immediately, with continued improvement as the skin’s renewal process unfolds.
What it won't do
PRX improves overall skin quality, but deeper acne scars, significant skin laxity and concerns requiring more intensive resurfacing may be better suited for treatments like SkinPen®, Sofwave™ or a traditional chemical peel. We’ll always recommend what makes the most sense for your skin and goals.
How often
A single treatment is perfect when you want an instant refresh and glow. For more progressive results, PRX can be performed as a series of treatments spaced approximately one week apart, followed by maintenance treatments as needed.
Good to know
Your visit, start to finish
PRX Derm Perfexion® is a versatile treatment suitable for all skin tones and an ideal choice when you want visible skin rejuvenation without needles or downtime. It can be used on the face, neck, décolleté and hands, making it perfect for improving skin quality beyond the face alone.
Before
- Pause retinoids and stronger exfoliating products for 48 to 72 hours before your appointment. Arrive with clean, makeup-free skin whenever possible.
During
- You may feel brief warmth or tingling as each layer is massaged into the skin. No needles or numbing are needed.
After
- Skin looks brighter, smoother and refreshed. Mild dryness or light flaking may occur over the next few days.
Please wait if you're pregnant or nursing, if you have a cold sore, broken skin or a rash in the area, or if you've recently had a sunburn, a strong resurfacing treatment or Accutane. If you're allergic to kojic acid, tell us first, because it's in the formula.
Questions
Frequently asked
Prefer to ask us directly? Call or text (239) 826‑6094 and we’ll be happy to help.
PRX Derm Perfexion® uses 33% TCA, but unlike a traditional chemical peel, it is designed to stimulate skin renewal without causing significant surface exfoliation. Most clients experience little to no visible peeling, although mild dryness or light flaking can occasionally occur.
Yes. PRX-T33 is the original name of the treatment, while PRX Derm Perfexion is the name used in the United States.
Most clients experience brief warmth or tingling as the formula is applied in layers. The sensation typically passes quickly, and there are no needles or numbing required.
A single treatment is perfect when you want an immediate refresh and glow. For more progressive results, PRX can be performed as a customized series, often spaced approximately one week apart. Your provider will recommend the best approach based on your skin and goals.
Many clients notice brighter, smoother and more refreshed-looking skin immediately after treatment. Improvements in overall skin quality and firmness can continue to develop as the skin’s renewal process unfolds.
Yes. PRX can be used on the face, neck, décolleté and hands, making it a great option for improving skin quality in areas that often show visible signs of aging.
Yes. PRX is suitable for all skin tones. Your provider will always evaluate your skin beforehand and customize the treatment appropriately.
PRX combines 33% TCA with hydrogen peroxide to stimulate skin renewal beneath the surface without creating the traditional peeling associated with TCA treatments. Kojic acid is also included to help improve uneven tone and brighten the complexion.
Yes. PRX can be strategically paired with treatments like SkinPen® microneedling or HydraFacial® for an added level of renewal and correction. Your provider will determine the best combination and timing based on your skin, concerns and treatment goals.



